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Imaging of Central Nervous System Involvement in Pediatric Hematologic Disorders
1Department of Pediatric Radiology, University of Health Sciences Umraniye Training and Research Hospital, İstanbul, Turkey.
Turkish Archives of Pediatrics
|July 5, 2022
Summary
This review details imaging findings for pediatric hematologic diseases affecting the central nervous system (CNS). It highlights the crucial role of radiological evaluation in diagnosing and managing these complex pediatric conditions.
Area of Science:
- Pediatric Hematology
- Neuroradiology
- Oncology
Background:
- Hematologic disorders and malignancies are frequent in children.
- The central nervous system (CNS) can be affected by both benign and malignant hematological conditions.
- Neurologic symptoms may arise from direct CNS involvement or treatment-related neurotoxicity.
Purpose of the Study:
- To describe the imaging findings of CNS involvement in pediatric hematologic diseases.
- To provide a comprehensive review of radiologic manifestations.
- To emphasize the importance of imaging in diagnosis and management.
Main Methods:
- Literature review of PubMed database (inception to March 2022).
- Inclusion of English-language articles.
- Use of archived radiological images from Picture Archiving and Communication Systems (PACS) for illustration.
Main Results:
- Detailed description of imaging findings associated with various pediatric hematologic diseases affecting the CNS.
- Correlation of radiologic findings with specific hematologic conditions.
- Illustrative examples from patient archives.
Conclusions:
- Radiological imaging plays a critical role in identifying and evaluating CNS involvement in pediatric hematologic diseases.
- Accurate interpretation of imaging findings aids in timely diagnosis and treatment planning.
- This review serves as a valuable resource for clinicians and radiologists.
