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Updated: Sep 6, 2025

Targeting Gray Rami Communicantes in Selective Chemical Lumbar Sympathectomy
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Celiac Plexus Cryoneurolysis.

Aron Chary1, Faramarz Edalat2

  • 1MidSouth Imaging, Vascular Interventional Physicians, Memphis, Tennessee.

Seminars in Interventional Radiology
|July 5, 2022
PubMed
Summary
This summary is machine-generated.

Celiac plexus neurolysis offers an alternative to opioids for chronic abdominal pain. This minimally invasive procedure, guided by CT scans, can improve patient quality of life with potentially fewer side effects than traditional methods.

Keywords:
celiac plexuscryoablationinterventional radiologymalignancyneurolysispain management

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Area of Science:

  • Interventional Radiology
  • Pain Management
  • Gastroenterology

Background:

  • Chronic upper abdominal pain from malignant and benign diseases poses a significant clinical challenge.
  • Opioid analgesics are common but associated with adverse effects from long-term use.
  • Celiac plexus neurolysis presents a minimally invasive alternative for palliative pain relief.

Purpose of the Study:

  • To evaluate celiac plexus neurolysis as a treatment for intractable chronic upper abdominal pain.
  • To compare different neurolysis techniques, including cryoablation, chemical, and thermal methods.

Main Methods:

  • Computed tomography (CT)-guided celiac plexus neurolysis.
  • Procedures performed using chemical agents (ethanol, phenol) or thermal ablation (cryoablation).
  • Accurate targeting of the celiac plexus to minimize risks to adjacent structures.

Main Results:

  • Celiac plexus neurolysis effectively provides palliative pain relief.
  • Cryoablation has emerged as a technique with potentially fewer side effects compared to historical methods.
  • Minimally invasive approach enhances patient quality of life.

Conclusions:

  • CT-guided celiac plexus neurolysis is a viable option for managing chronic upper abdominal pain.
  • Cryoablation offers a promising alternative with a favorable side effect profile.
  • This intervention improves quality of life for patients with intractable abdominal pain.