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Updated: Sep 6, 2025

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Frailty: Past, present, and future?

Dongmin Kwak1, LaDora V Thompson2

  • 1Division of Sport Science, Hanyang University, Ansan, South Korea.

Sports Medicine and Health Science
|July 5, 2022
PubMed
Summary
This summary is machine-generated.

Frailty is a growing global health concern in older adults, increasing risks for falls and mortality. Early detection via screening tools and interventions like physical activity are crucial for prevention and management.

Keywords:
2018 PAGAC Scientific ReportFrailty phenotypeIntrinsic capacityMulticomponent physical activity programsPhysical activity guidelines

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Area of Science:

  • Gerontology and Geriatric Medicine
  • Public Health
  • Exercise Science

Background:

  • Increasing global prevalence of frailty in older adults.
  • Frailty is associated with adverse health outcomes like falls, hospitalizations, and mortality.
  • Frailty is considered a preventable condition, necessitating early identification.

Purpose of the Study:

  • Provide a historical perspective on frailty research.
  • Outline frailty pathophysiology, screening tools, and physical activity benefits.
  • Emphasize early frailty detection and the value of physical activity interventions.

Main Methods:

  • Review of scientific literature on frailty.
  • Analysis of underlying pathophysiology and physiological systems.
  • Evaluation of frailty screening tools and physical activity evidence.

Main Results:

  • Frailty research has advanced significantly, incorporating aging hallmarks and resilience concepts.
  • Valid and reliable screening tools are available for frailty identification.
  • Physical activity is a key intervention for managing frailty.

Conclusions:

  • Early detection of frailty is vital for implementing targeted interventions.
  • Physical activity programs offer significant benefits for older adults with frailty.
  • Continued research and clinical focus on frailty prevention and management are essential.