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Updated: Sep 5, 2025

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
An Efficient Rotation Forest-Based Ensemble Approach for Predicting Severity of Parkinson's Disease
Saeid Sheikhi1, Mohammad Taghi Kheirabadi1
1Department of Computer, Islamic Azad University, Gorgan Branch, Gorgan, Iran.
Abstract:
Parkinson's disease (PD) is a neurodegenerative nervous system disorder that mainly affects body movement, and it is one of the most common diseases, particularly in elderly individuals. This paper proposes a new machine learning approach to predict Parkinson's disease severity using UCI's Parkinson's telemonitoring voice dataset. The proposed method analyses the patient's voice data and classifies them into "severe" and "nonsevere" classes. At first, a subset of features was selected, then a novel approach with a combination of Rotation Forest and Random Forest was applied on selected features to determine each patient's disease severity. Analysis of the experimental results shows that the proposed approach can detect the severity of PD patients in the early stages. Moreover, the proposed model is compared with several algorithms, and the results indicate that the model is highly successful in classifying records and outperformed the other methods concerning classification accuracy and F1-measure rate.
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