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Pediatric Invasive Pneumococcal Disease (IPD) in Yogyakarta, Indonesia: A Case Series
Eggi Arguni1, Conroy Surya Wijaya1, Ratni Indrawanti1
1Department of Child Health, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr Sardjito General Hospital, Yogyakarta, Indonesia.
Insights
Invasive pneumococcal disease (IPD) in Indonesian children is underreported. This case series highlights risk factors, antibiotic resistance, and the crucial need for pneumococcal vaccination in at-risk children.
Area of Science:
- Pediatrics
- Infectious Diseases
- Microbiology
Background:
- Invasive pneumococcal disease (IPD) poses a significant global health challenge, especially in developing nations.
- Limited data exists on the epidemiology and clinical characteristics of IPD among Indonesian children.
- Understanding local patterns is crucial for effective disease management and prevention strategies.
Abstract:
Given the fact that invasive pneumococcal disease (IPD) has a high clinical burden, particularly among children in developing countries, data on its occurrence and clinical profile in Indonesia is still insufficient. We presented 3 cases of IPD in children who were admitted to Dr. Sardjito General Hospital, Yogyakarta, Indonesia between 2016 and 2019. While our first 2 patients had milder course of disease, our third patient who presented with meningoencephalitis had poor outcome. Risk factors shown in our cases were young age and malignancy history. Multiple antibiotic resistance was observed in our isolates. The fact that none of our patients have received pneumococcal vaccination marks the necessity of this vaccine especially for at-risk children.
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