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A Reversible Lesion of the Corpus Callosum Associated With Bacterial Meningitis

Yasmine Mimouni1, Rim Tazi1, Amal Miqdadi2

  • 1Neurology, Cheikh Khalifa Ibn Zayed Hospital, Mohamed VI University of Health Sciences (UM6SS), Casablanca, MAR.

Cureus
|July 5, 2022
PubMed

Insights

A rare case of Pseudomonas aeruginosa meningitis in a young woman, linked to spinal anesthesia, caused an isolated brain lesion that resolved with antibiotics. This highlights the importance of considering neurosurgical history in meningitis diagnosis.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Radiology

Background:

  • Post-procedural meningitis is a rare but serious complication.
  • Pseudomonas aeruginosa is an opportunistic gram-negative bacterium that can cause severe infections.

Observation:

  • A 22-year-old female presented with headaches and nausea.
  • Brain MRI revealed an isolated lesion in the splenium of the corpus callosum (SCC).
  • Lumbar puncture confirmed Pseudomonas aeruginosa meningitis.

Findings:

  • The patient had undergone spinal anesthesia for a cesarean section 20 days prior.
  • Antibiotic therapy was initiated promptly upon diagnosis.
  • The SCC lesion resolved spontaneously within one month, as confirmed by follow-up MRI.

Implications:

  • This case underscores the potential for Pseudomonas aeruginosa to cause meningitis following neurosurgical procedures or spinal anesthesia.
  • Clinicians should inquire about recent invasive procedures in patients presenting with meningitis.
  • Early diagnosis and appropriate antibiotic treatment are crucial for favorable outcomes.
Keywords:
corpus callosumgram-negative meningitismeningitisobstetrical anesthesiapseudomonas aeruginosaspinal anesthesiasplenium of the corpus callosum

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