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The Japanese lead extraction registry (J-LEX): Annual report 2020
Morio Shoda1, Kengo Kusano2, Masahiko Goya3
1Clinical Research Division of Heart Rhythm Management, Department of Cardiology Tokyo Women's Medical University Tokyo Japan.
Insights
The Japanese lead extraction registry (J-LEX) reported on 785 transvenous lead extraction (TLE) procedures in 2020. While TLE success rates remain high, a slight increase in perioperative complications was noted compared to 2019.
Area of Science:
- Cardiology
- Medical Device Technology
- Public Health
Background:
- The Japanese Heart Rhythm Society established the Japanese lead extraction registry (J-LEX) in 2018.
- J-LEX is a mandatory, multi-center, prospective, observational registry for transvenous lead extraction (TLE).
- The 2020 report details the second annual data collection from the registry.
Purpose of the Study:
- To report the findings from the second annual data collection of the Japanese lead extraction registry (J-LEX).
- To analyze trends in transvenous lead extraction (TLE) procedures, indications, success rates, and complications in Japan.
- To compare outcomes from 2020 with previous years, considering the impact of the COVID-19 pandemic.
Main Methods:
- Prospective, observational data collection from 75 hospitals participating in the J-LEX registry.
- Inclusion of 785 transvenous lead extraction (TLE) cases from 2020.
- Analysis of patient demographics, procedure settings, TLE indications, lead implantation duration, procedural success, and perioperative complications.
Main Results:
- TLE procedures were performed on patients with an average age of 71.7 years, predominantly male (72.5%).
- The primary indication for TLE was infection (62.8%), with most procedures classified as guideline class-I (67.4%) or class-IIa (23.8%).
- Complete lead removal was achieved in 96.6%, with a clinical success rate of 98.1%. Perioperative complications occurred in 7.1% of patients, with a total of four in-hospital deaths. A slight increase in complications was observed compared to 2019.
Conclusions:
- The 2020 J-LEX report indicates a growing number of transvenous lead extraction (TLE) procedures in Japan, even during the COVID-19 pandemic.
- High rates of complete lead removal and clinical success were maintained.
- A modest increase in perioperative complications warrants continued monitoring and analysis.
Abstract:
The Japanese Heart Rhythm Society established a nationwide, mandatory, multi-center, prospective, observational registry of transvenous lead extraction (TLE) named the Japanese lead extraction registry (J-LEX) in 2018. We have published the first annual report of J-LEX with 661 cases from 42 hospitals. The second annual report of J-LEX in 2020 enrolled increased numbers of 785 cases from 75 hospitals. TLE procedure was attempted on patients with an average age of 71.7 years old, male in 72.5% in the hybrid operating room in 57.9%, and in standard OR with a C-arm fluoroscope in 18.7%. The indication of TLE was an infection in 62.8% and the guideline classification was class-I in 67.4% and class-IIa in 23.8%. The average implantation duration of target leads was 7.9 years. Complete removal was achieved in 96.6% of the target leads and clinical success in 98.1% of the patients. Perioperative complications were observed in 7.1% of the patients. One patient died during a TLE operation and the other three patients died in-hospital (cardiac death in one patient and non-cardiac in two patients). Although the annual J-LEX report in 2020 demonstrated an increased number of TLE procedures despite the first pandemic year of coronavirus disease-2019 (COVID-19), perioperative complications increased a little in comparison with J-LEX 2019.
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