Related Experiment Video
Updated: Sep 5, 2025
Author Spotlight: Advancing Immune Monitoring in Critical Care Patients Using Whole Blood Assays
Published on: September 20, 2024
Comparison of some hematological parameters between male and female patients infected with COVID-19
Hayder H Abed1, Ahmed Ghdhban Al-Ziaydi2, Ihab Abbas Taher1
1Chemistry and Biochemistry Division, Faculty of Medicine, Al Muthanna University, Samawah, Iraq.
Insights
COVID-19 patients show higher D-dimer and ferritin levels in males compared to females. Other blood parameters like CRP and WBCs did not show significant gender-based differences in this study.
Area of Science:
- Medical research
- Infectious diseases
- Hematology
Background:
- COVID-19 is a global pandemic requiring continuous patient monitoring.
- Limited medical resources in some regions necessitate efficient patient status tracking.
- Blood parameters are crucial for monitoring COVID-19 progression.
Purpose of the Study:
- To compare serum D-dimer, Ferritin, CRP, WBCs, Lymphocytes, and Neutrophils levels.
- To investigate gender-based differences in these blood parameters among COVID-19 patients.
Main Methods:
- Evaluated D-dimer, Ferritin, CRP, WBCs, lymphocytes, and neutrophils.
- Analyzed data from 116 COVID-19 patients (68 males, 48 females).
Main Results:
- Significantly higher D-dimer levels observed in males (1618 ± 247.7 ng/ml) versus females (684.5 ± 53.69 ng/ml).
- Significantly higher Ferritin levels noted in males (525.6 ± 69.55 μg/L) versus females (254.1 ± 33.73 μg/L).
- No significant gender differences found in CRP, LDH, WBCs, Lymphocytes, or Neutrophils, despite abnormal values.
Conclusions:
- Male COVID-19 patients exhibit significantly elevated D-dimer and Ferritin levels compared to females.
- No significant gender-based disparities were found in CRP, LDH, WBCs, Lymphocytes, or Neutrophils.
Background:
COVID-19 is a highly contagious virus that is rapidly spreading across the world. As the number of COVID-19 patients is quickly rising, and certain nations and areas, such as the third world countries, lack the medical resources, it is critical to track and monitor a patient's status using blood parameters on regular testing. The aim of this study is to compare the serum D-dimer levels, Ferritin, CRP, WBCs, Lymphocytes, and Neutrophils in male and female patients infected with COVID-19.
Objective And Methods:
The study procedure includes evaluating the D-dimer level, Ferritin, CRP, WBCs, lymphocytes, and neutrophils in 116 patients infected with COVID-19 (48 Females and 68 Males).
Result:
The result of this study shows a significant increase in the D-dimer level in males 1618 ± 247.7 ng/ml compared to females 684.5 ± 53.69 ng/ml and a significant increase in Ferritin level in males 525.6 ± 69.55 μg/L compared to females 254.1 ± 33.73 μg/L. However, no other significant change is seen in the other parameters (CRP, LDH, and WBCs, L, and N) although all of these parameters are abnormal, compared to the normal reference values.
Conclusion:
This study concludes that there is a significant increase in the D-dimer and Ferritin concentrations in male patients compared to female patients, who were infected with COVID-19. Also there are no significant differences in other parameters (CRP, LDH, WBCs, L, and N) between male and female patients.
