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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
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Evolution of adverse drug reactions reporting systems: paper based to software based
M T Madhushika1, T P Weerarathna2, P L G C Liyanage3
1Department of Pharmacology, Faculty of Medicine, University of Ruhuna, Matara, Sri Lanka. mtmadhushika@med.ruh.ac.lk.
European Journal of Clinical Pharmacology
|July 5, 2022
Summary
Adverse Drug Reactions (ADR) reporting systems are crucial for drug safety. Enhancing these systems with new technologies is vital for effective pharmacovigilance and reducing healthcare burdens.
Area of Science:
- Pharmacovigilance
- Drug Safety
- Healthcare Systems
Background:
- Adverse Drug Reactions (ADRs) impose significant clinical and economic burdens on national healthcare systems.
- Effective pharmacovigilance relies on robust systems for detecting and reporting ADRs post-market.
- Current ADR reporting methods vary globally, with direct reporting by healthcare professionals being common.
Purpose of the Study:
- To provide a comprehensive overview of global ADR reporting systems.
- To examine the evolution of ADR reporting strategies over time.
- To highlight the potential of new technologies in improving ADR detection and reporting.
Main Methods:
- Systematic literature review utilizing PubMed and the Cochrane database.
- Inclusion of original articles, and reports from WHO, FDA, and the Institute of Medicine.
- Analysis of various ADR reporting methodologies employed worldwide.
Main Results:
- Direct reporting by healthcare professionals is a widely adopted method for ADR surveillance.
- Many countries have national regulatory bodies overseeing ADR reporting.
- Emerging technologies offer significant potential to enhance ADR reporting systems, particularly in regions with existing limitations.
Conclusions:
- Implementing and adopting advanced technologies is essential for strengthening ADR monitoring and reporting.
- An effective national pharmacovigilance system necessitates the integration of newer technologies.
- Continuous improvement of ADR reporting mechanisms is critical for public health and drug safety.
Keywords:
Adverse drug reaction reporting systemsDrug informationPharmacovigilancePost-marketing surveillanceMore Related Videos
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