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Published on: April 20, 2018
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ONS Guidelines™ to Support Patient Adherence to Oral Anticancer Medications
Sarah M Belcher1, Emily Mackler2, Benyam Muluneh3
1University of Pittsburgh.
Oncology Nursing Forum
|July 5, 2022
Summary
This guideline offers strategies to improve patient adherence to oral anticancer medications (OAMs). Key recommendations include risk assessment, education, and structured follow-up programs for better cancer treatment outcomes.
Area of Science:
- Oncology
- Evidence-Based Practice
- Patient Adherence
Background:
- Cancer treatment is increasingly shifting to home settings.
- Effective patient support for oral anticancer medications (OAMs) is crucial.
- Adherence to OAMs significantly impacts treatment efficacy.
Purpose of the Study:
- To provide an evidence-based guideline for supporting patient adherence to OAMs.
- To outline interventions and processes for clinicians and patients.
- To address the growing need for home-based cancer care support.
Main Methods:
- Development of a clinical practice guideline by healthcare professionals and patient representatives.
- Adherence to GRADE (Grading of Recommendations Assessment, Development, and Evaluation) methodology for trustworthy guidelines.
- Systematic review of evidence using Cochrane Risk of Bias 2 tool and GRADE certainty assessment.
Main Results:
- Recommendations include adherence risk assessment and patient education.
- Ongoing assessment, proactive follow-up, coaching, and motivational interviewing are suggested.
- Implementation of a structured OAM program is recommended alongside usual care.
Conclusions:
- Interventions and programs are essential to support patients on OAMs in home settings.
- Structured OAM programs can enhance patient adherence and potentially improve outcomes.
- This guideline provides a framework for optimizing OAM therapy management.
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