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Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
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Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

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Cardiac magnetic resonance imaging of arrhythmogenic cardiomyopathy: evolving diagnostic perspectives

Alberto Cipriani1,2, Giulia Mattesi2, Riccardo Bariani1

  • 1Department of Cardio-Thoraco-Vascular Sciences and Public Health, University of Padua, Via Giustiniani, 2, 35128, Padua, Italy.

European Radiology
|July 5, 2022
PubMed

Insights

Arrhythmogenic cardiomyopathy (ACM) is a genetic heart disease. Cardiac magnetic resonance (CMR) is now the preferred imaging technique for diagnosing all ACM phenotypes, including left ventricular variants, using updated criteria.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Genetics

Background:

  • Arrhythmogenic cardiomyopathy (ACM) is a genetic heart muscle disease featuring fibro-fatty replacement.
  • It is linked to ventricular arrhythmias and sudden cardiac death.
  • ACM presents with right ventricular, left dominant, or biventricular phenotypes.

Purpose of the Study:

  • To review the role of cardiac magnetic resonance (CMR) in diagnosing the full spectrum of ACM phenotypes.
  • To highlight updated diagnostic criteria (2020 Padua Criteria) and CMR's importance.
  • To detail ACM-specific CMR protocols and discuss imaging technique strengths and weaknesses.

Main Methods:

  • Review of current literature on cardiac magnetic resonance in arrhythmogenic cardiomyopathy.
  • Focus on the 2020 Padua Criteria for ACM diagnosis.
  • Inclusion of ACM-specific CMR protocols and comparative analysis of imaging modalities.

Main Results:

  • Cardiac magnetic resonance (CMR) is the imaging technique of choice for diagnosing all ACM phenotypes, including left ventricular variants.
  • CMR offers detailed morpho-functional and tissue characterization of both right and left ventricles.
  • The review outlines the supplemental value of CMR in characterizing disease variants.

Conclusions:

  • Cardiac magnetic resonance (CMR) plays a pivotal role in the updated diagnosis of arrhythmogenic cardiomyopathy (ACM).
  • CMR enables comprehensive evaluation across all ACM phenotypes, aiding in diagnosis and characterization.
  • Understanding CMR findings is crucial for assessing the prognostic significance in ACM patients.

Keywords:
Arrhythmogenic right ventricular dysplasiaMagnetic resonance imagingSudden death

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