[New drugs for small animals in 2021]

In 2021, 8 novel pharmaceutical agents for small animals were released on the German market: The specific monoclonal antibodies bedinvetmab (Librela^®) and frunevetmab (Solensia^®), the cyclooxygenase-2 inhibitor enflioxib (Daxocox^®), the ectoparasitic esafoxolaner (NexGard^® Combo) of the isoxazoline group, the anti-haemorrhagic etamsylate (Hemosilate), the antidepressant mirtazapine (Mirataz^®), the alpha-selective sympathomimetic tetryzoline for ophthalmic use (Zolicep^®) and the cytostatic tigilanol tiglate (Stelfonta^®). No active substance received an animal species extension. In addition, for small animals, there were new releases of two agents in a novel pharmaceutical formulation (cefalexin, gentamicin), five drugs with a new content of the active ingredient (metronidazole, pimobendan, thiamazole, tramadol, trilostane), one veterinary drug with a new combination of active ingredients (lotilaner + milbemycin oxime), one drug with a new route of administration (propofol) and furthermore two temporarily non-available active ingredients for certain animal species were reapproved in new drugs (levothyroxine for cats and oxytetracycline for dogs and cats).