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Related Concept Videos

Assessing Blood pressure using a doppler ultrasound01:19

Assessing Blood pressure using a doppler ultrasound

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To obtain accurate blood pressure measurements in clinical settings, especially when traditional methods are insufficient, healthcare professionals utilize the Doppler ultrasound technique. This method uses high-frequency sound waves to detect blood flow within the arteries, which is crucial for patients with conditions that complicate circulatory system assessment.
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
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Related Experiment Video

Updated: Sep 5, 2025

Three-Dimensional Ultrasonic Needle Tip Tracking with a Fiber-Optic Ultrasound Receiver
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Pulsed-wave Doppler for ultrasound-based tip location using bubble test: A pilot study.

Antonio Gidaro1, Francesco Casella1, Chiara Cogliati1

  • 1Department of Biomedical and Clinical Sciences "Luigi Sacco," University of Milan, Luigi Sacco Hospital, Milan, Italy.

The Journal of Vascular Access
|July 6, 2022
PubMed
Summary

The MicroBubbles Time test (MBT) with pulse wave Doppler (PW) shows excellent agreement with the reference standard for central venous catheter tip location. This technique offers a reliable method for confirming catheter placement, improving patient safety.

Keywords:
Central venous catheters (CVCs)MicroBubbles Time (MBT)MicroBubbles Time with pulse Doppler (MBT-PW)contrast enhanced ultrasound (CEUS)microembolic signals (MES)tip’s location

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Area of Science:

  • Medical Imaging
  • Ultrasound Technology
  • Cardiovascular Procedures

Background:

  • Central venous catheters (CVCs) require precise tip location for safety and efficacy.
  • Current methods like Intracavitary ECG (IC-ECG) and chest X-ray have limitations.
  • The MicroBubbles Time test (MBT) using echocardiography is a promising alternative but lacks standardization, particularly regarding timing.

Purpose of the Study:

  • To establish agreement between MBT with pulse wave Doppler (MBT-PW) and the reference standard (IC-ECG) for CVC tip location.
  • To compare MBT-PW with the standard MBT technique.
  • To evaluate inter-observer variability in microembolic signal (MES) detection and grading.

Main Methods:

  • Pilot study involving eight patients undergoing CVC placement.
  • Simultaneous acquisition of MBT and MBT-PW, with sample volume at the tricuspid valve to detect MES.
  • Comparison of MBT-PW and MBT against the reference standard IC-ECG for tip confirmation.

Main Results:

  • Excellent agreement (Cohen's kappa = 1) was found between MBT-PW and IC-ECG, and between MBT-PW and MBT.
  • Microbubbles were detected within the first heart beat in all patients for both MBT-PW and MBT.
  • High inter-observer agreement was observed for MBT-PW evaluation (Cohen's kappa = 1) and substantial agreement for MES grading (Fleiss' Kappa = 0.704).

Conclusions:

  • MBT-PW demonstrates strong agreement with the established IC-ECG standard for CVC tip localization.
  • The MBT-PW technique is a reliable and reproducible method for confirming CVC tip position.
  • This ultrasound-based approach offers a standardized and effective alternative for CVC tip verification.