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Determination of dexamethasone dose for cortisol suppression in adult common marmosets (Callithrix jacchus)
Kimberley A Phillips1,2, Matthew Lopez1,2, Adam B Salmon3,4
1Department of Psychology, Trinity University, San Antonio, Texas, USA.
Journal of Medical Primatology
|July 6, 2022
Abstract:
We conducted a dose-response study of dexamethasone to investigate an optimal dexamethasone suppression test for common marmosets. Twelve marmosets received 0.1, 0.5, or 1.0 mg/kg dexamethasone. Doses of 0.5 and 1.0 mg/kg both suppressed endogenous cortisol for at least 18 h with greater individual variability in the lower 0.5 mg/kg dose.

