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Choroidal changes in posterior microphthalmos.

Ramesh Venkatesh¹, Sahil Arora¹, Nikitha Gurram Reddy¹

¹Department of Retina and Vitreous, Narayana Nethralaya, Bengaluru, Karnataka, India.

European Journal of Ophthalmology

|July 6, 2022

Summary

This summary is machine-generated.

Posterior microphthalmos (PM) involves significant choroidal variations, including thickened retina and choroid, and altered peripheral vasculature. Vortex veins were not visualized in affected eyes.

Keywords:

Posterior microphthalmos choroid indocyanine green angiography optical coherence tomography

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Area of Science:

Ophthalmology
Retinal Imaging
Choroidal Anatomy

Background:

Posterior microphthalmos (PM) is a rare condition characterized by a small eye with a normal or near-normal anterior segment.
Understanding the underlying structural changes, particularly in the posterior segment, is crucial for managing PM.

Observation:

This observational case series investigated choroidal variations in two patients with posterior microphthalmos using multimodal imaging.
Techniques included ultrawide field fundus photography, optical coherence tomography (OCT), and indocyanine green angiography (ICGA).

Findings:

Multimodal imaging revealed thickened retina and choroid in all four affected eyes.
Retinal papillomacular folds (RPMF) were consistently observed.
Indocyanine green angiography showed normal dye transit times but revealed reduced peripheral choroidal vasculature anterior to the equator and increased density posterior to the equator. Vortex veins were not visualized.

Implications:

Choroidal structure and vascular patterns are significantly altered in posterior microphthalmos.
These findings highlight the need for further research in larger patient cohorts to validate and expand upon these observations.
Detailed understanding of choroidal changes may inform future diagnostic and therapeutic strategies for PM.