Related Experiment Video

Updated: Sep 5, 2025

Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis
04:36

Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis

Published on: October 2, 2020

2.3K

COVID-19-related clinical outcomes among Korean hemodialysis patients

Hayne Cho Park1,2, Young-Ki Lee1,2, Eunsil Ko3

  • 1Department of Internal Medicine, Hallym University Kangnam Sacred Heart Hospital, Seoul, Republic of Korea.

Kidney Research and Clinical Practice
|July 6, 2022
PubMed

Insights

Patients on hemodialysis (HD) face significantly higher mortality risks from COVID-19. This study highlights the increased vulnerability of HD patients, emphasizing the need for targeted care during viral epidemics.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Epidemiology

Background:

  • Hemodialysis (HD) patients exhibit heightened vulnerability during viral epidemics, with elevated mortality rates compared to non-chronic kidney disease (CKD) individuals.
  • This study focuses on clinical outcomes and risk factors in Korean HD patients diagnosed with coronavirus disease 2019 (COVID-19).

Purpose of the Study:

  • To evaluate the clinical outcomes of COVID-19 in hemodialysis patients.
  • To identify factors associated with adverse clinical outcomes in this vulnerable population.
  • To compare the risks faced by HD patients with the general non-CKD population.

Main Methods:

  • A retrospective cohort study analyzed clinical data from 380 confirmed COVID-19 HD patients across 206 facilities between February 2020 and November 2021.
  • Data were collected via a nephrologist self-report survey by the COVID-19 Task Force Team.
  • Composite outcomes (in-hospital mortality, ICU admission, mechanical ventilation) were assessed, with risk factor analysis compared against the Korea Disease Control and Prevention Agency's non-CKD COVID-19 database.

Main Results:

  • The most common symptoms were fever (49.5%) and cough (25.7%).
  • The overall in-hospital fatality rate was 22.4%, rising to 64.7% for ICU admissions.
  • HD patients demonstrated a significantly higher risk of in-hospital mortality (HR, 2.07) and composite adverse outcomes (HR, 3.50) compared to the non-CKD population.

Conclusions:

  • Hemodialysis patients face a substantially increased risk of mortality and severe morbidity from COVID-19.
  • Older HD patients or those presenting with specific symptoms require heightened clinical vigilance and specialized care protocols.
Abstract

Keywords:
COVID-19DialysisMortalityRisk factors

More Related Videos

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice06:27

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

Published on: July 20, 2022

2.7K
A Murine Model of Hemodialysis Access-Related Hand Dysfunction08:39

A Murine Model of Hemodialysis Access-Related Hand Dysfunction

Published on: May 31, 2022

1.8K

Related Concept Videos

Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
124
Hemodialysis III: Nursing Management01:25

Hemodialysis III: Nursing Management

The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this...
170
Dialysis01:27

Dialysis

Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
462
Hemodialysis I: Introduction01:25

Hemodialysis I: Introduction

Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
271
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
80
Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
83