[Association between Gestational Diabetes Mellitus and Postpartum Depressive Episode]

Area of Science:

• Obstetrics
• Perinatology
• Psychiatry

Background:

• Gestational diabetes mellitus (GDM) is a common pregnancy complication.
• Postpartum depression (PPD) affects a significant number of new mothers.
• Understanding the relationship between GDM and PPD is crucial for maternal mental health.

Purpose of the Study:

• To investigate the association between gestational diabetes mellitus (GDM) and postpartum depressive (PPD) episodes.
• To identify the influencing factors of PPD in pregnant women.
• To explore the relationship between GDM management and PPD.

Main Methods:

• Clinical data from pregnant women were collected.
• Gestational diabetes mellitus was diagnosed using OGTT and HbA1c in the second trimester, and fasting blood glucose and GA in the third trimester.
• Postpartum depressive episodes and anxiety disorders were diagnosed using the MINI 5.0 Chinese version within 42 days after delivery.

Main Results:

• No significant differences in GDM markers or PPD incidence were found between women with and without PPD.
• Postpartum generalized anxiety disorder, obsessive-compulsive disorder, and a history of mental disorder before pregnancy were identified as risk factors for PPD.
• No significant differences in third-trimester glucose levels, PPD incidence, or comorbidities were observed between pregnant women with and without GDM.

Conclusions:

• Gestational diabetes mellitus is not associated with postpartum depressive episodes under routine blood glucose management.
• A history of mental disorder before pregnancy is a significant risk factor for postpartum depression.
• Pregnant women with a history of mental disorders require special attention during the postpartum period.