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[Abdominal Aortic Aneurysm:Pathological Mechanism and Animal Model]

Hui Fu1, Can-Can Zhou1, Dong-Jie Li1

  • 1Department of Pharmacy,Shanghai Tenth People's Hospital,Tongji University School of Medicine,Tongji University,Shanghai 200072,China.

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
|July 6, 2022
PubMed

Keywords:
abdominal aortic aneurysmanimal modelshigh-risk factorspathologic featurestherapies

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An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
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