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Global Pattern and Trends in Penile Cancer Incidence: Population-Based Study
Leiwen Fu1, Tian Tian1, Kai Yao2
1School of Public Health (Shenzhen), Sun Yat-sen University, Guangzhou, Guangdong, China.
Penile cancer incidence and mortality are rising globally, particularly in European nations. Public health strategies focusing on hygiene and HPV vaccination are recommended to reduce the disease burden.
Area of Science:
- Oncology
- Epidemiology
- Public Health
Background:
- Penile cancer is a rare malignancy with increasing global incidence and mortality.
- This trend necessitates updated epidemiological assessments.
Purpose of the Study:
- To evaluate recent penile cancer incidence and mortality rates.
- To analyze penile cancer incidence trends across diverse global populations.
Main Methods:
- Utilized GLOBOCAN database for 2020 age-standardized incidence and mortality rates (ASIR and ASMR).
- Analyzed incidence trends (1973-2012) using CI5plus and NORDCAN databases.
- Employed joinpoint regression to calculate average annual percentage change in ASIR.
Main Results:
- Global ASIR was 0.80/100,000 and ASMR was 0.29/100,000 in 2020, with 36,068 new cases and 13,211 deaths.
- No significant correlation found between penile cancer rates and the Human Development Index.
- Fifteen countries, primarily in Europe, showed increasing penile cancer ASIR.
Conclusions:
- While developing nations still have higher rates, penile cancer incidence is rising in Europe.
- Interventions such as improved penile hygiene and HPV vaccination are crucial for mitigating disease burden.
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