Related Experiment Video

Updated: Sep 5, 2025

Femoral Vascular Graft Implantation in a Swine Model to Test Small-Diameter Vascular Grafts
06:09

Femoral Vascular Graft Implantation in a Swine Model to Test Small-Diameter Vascular Grafts

Published on: July 8, 2025

182

A Case of Vascular Graft Infection Caused by Haemophilus parainfluenzae

Ayako Okuhama1, Yuta Murai2, Masahiro Ishikane1

  • 1Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.

Open Forum Infectious Diseases
|July 7, 2022
PubMed

Insights

Haemophilus parainfluenzae, a common airway bacterium, can cause serious infections. This case highlights a rare vascular graft infection occurring years after aortic dissection surgery.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Cardiovascular Surgery

Background:

  • Haemophilus parainfluenzae is a commensal bacterium of the human upper respiratory tract.
  • While typically benign, H. parainfluenzae can occasionally lead to invasive infections like endocarditis.

Observation:

  • A 68-year-old Japanese male developed a vascular graft infection.
  • The infection was attributed to H. parainfluenzae.
  • The patient had undergone surgery for chronic aortic dissection four years prior.

Findings:

  • This case demonstrates a delayed vascular graft infection caused by H. parainfluenzae.
  • The bacterium, usually a commensal, acted as a pathogen in this immunocompetent host.

Implications:

  • Highlights the potential for H. parainfluenzae to cause late-onset graft infections.
  • Suggests vigilance for unusual pathogens in patients with vascular grafts.
  • Underscores the importance of considering normal flora in complex post-surgical infections.
Keywords:
oral suppressive therapypseudoaneurysmvascular graft infection

More Related Videos

A Modified Heterotopic Swine Hind Limb Transplant Model for Translational Vascularized Composite Allotransplantation VCA Research09:09

A Modified Heterotopic Swine Hind Limb Transplant Model for Translational Vascularized Composite Allotransplantation VCA Research

Published on: October 14, 2013

12.6K
Implantation of Inferior Vena Cava Interposition Graft in Mouse Model12:39

Implantation of Inferior Vena Cava Interposition Graft in Mouse Model

Published on: June 4, 2014

12.0K

Related Concept Videos

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
4.4K
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
25
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
22
Hemodialysis I: Introduction01:25

Hemodialysis I: Introduction

Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
271
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.2K