Related Experiment Video

Updated: Sep 5, 2025

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

10.5K

Poor Asthma Control in Schoolchildren May Lead to Lower Lung Function Trajectory from Childhood to Early Adulthood: A

Shingo Tsuneyoshi1, Tomotaka Kawayama1, Jun Sasaki1

  • 1Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan.

Journal of Asthma and Allergy
|July 7, 2022
PubMed

Insights

Poor childhood asthma control is linked to reduced lung function and obstructive patterns in young adults. Early intervention is crucial for preventing long-term respiratory issues in children with asthma.

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Medicine
  • Public Health

Background:

  • Childhood asthma is a known risk factor for adult lung function disorders.
  • The specific impact of childhood asthma control levels on lung function growth in early adulthood remains unclear, particularly in Japan.

Purpose of the Study:

  • To investigate the correlation between childhood asthma control levels and lung function growth into early adulthood.
  • To assess the long-term respiratory health outcomes associated with different asthma control levels in children.

Main Methods:

  • A cohort of 505 children with asthma (aged 6-17 years) was analyzed.
  • Children were categorized into poor and good asthma control groups.
  • Lung function parameters, including forced expiratory volume in 1 second (FEV1), were compared between groups, and linear regression models were used to assess growth trends.

Main Results:

  • Children with poor asthma control exhibited significantly lower predicted FEV1 values compared to those with good control.
  • No significant between-group differences were found in the slopes of lung function growth.
  • A substantially higher proportion of young adults with obstructive ventilatory patterns were observed in the poor asthma control group compared to the good control group.

Conclusions:

  • Poor asthma control during childhood is associated with the development of lung function disorders, including obstructive ventilatory patterns, in early adulthood.
  • These findings underscore the critical importance of achieving and maintaining good asthma control in school-aged children to prevent long-term respiratory morbidity.
Abstract

Keywords:
Japaneseairflow limitationchildhood asthmaschool-age childrentransition

More Related Videos

Conducting Respiratory Oscillometry in an Outpatient Setting14:49

Conducting Respiratory Oscillometry in an Outpatient Setting

Published on: April 8, 2022

7.4K
Methodology for Sputum Induction and Laboratory Processing13:28

Methodology for Sputum Induction and Laboratory Processing

Published on: December 17, 2017

27.8K

Related Concept Videos

Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
560
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.8K
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.6K
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
2.6K
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.8K
Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
3.3K