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Updated: Sep 5, 2025

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Published on: March 30, 2015
Primary signet-ring cell carcinoma of the renal pelvis: An autopsy case
Heisuke Iijima1, Hiroaki Murata1, Shinnosuke Oishi1
1Department of Urology Yaizu City Hospital Yaizu Shizuoka Japan.
Introduction:
Signet-ring cell carcinoma is an extremely rare histological variant of upper urinary tract carcinoma, associated with poor prognosis.
Case Presentation:
We report a case of a 75-year-old female diagnosed with left primary upper urinary tract signet-ring cell carcinoma, initially treated with surgery. Post-surgical development of multifocal metastases was followed by a devastating clinical course. An autopsy confirmed the tumor's primary origin in the upper urinary tract.
Conclusion:
We experienced a case of upper urinary tract signet-ring cell carcinoma, with a rare opportunity to thoroughly confirm its primary site with an autopsy.

