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Updated: Sep 5, 2025

Forward Genetic Approaches in Chlamydia trachomatis
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CT295 Is Chlamydia trachomatis' Phosphoglucomutase and a Type 3 Secretion Substrate

Sébastien Triboulet1, Maimouna D N'Gadjaga1,2, Béatrice Niragire1

  • 1Institut Pasteur, Université Paris Cité, CNRS UMR3691, Unité de Biologie Cellulaire de l'Infection Microbienne, Paris, France.

Frontiers in Cellular and Infection Microbiology
|July 7, 2022
PubMed
Summary

Chlamydia trachomatis bacteria convert stored glycogen into usable glucose-6-phosphate via a bacterial phosphoglucomutase (PGM). This process, facilitated by a type three secretion (T3S) signal, shapes glycogen metabolism in Chlamydiaceae.

Keywords:
Chlamydiaglycogen, metabolismphosphoglucomutase (PGM)secretion signaltype 3 secreted effectors

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