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Intraparenchymal Hemorrhage: A Fatal Presentation of Undiagnosed Acute Myelogenous Leukemia

Rachelle Hamadi1, Marc Assaad1, Juda Zurndorfer2

  • 1Internal Medicine, Staten Island University Hospital, New York City, USA.

Cureus
|July 7, 2022
PubMed

We present the case of a 73-year-old patient who was admitted to the neurocritical care unit with spontaneous intracerebral hemorrhage (ICH). Upon further investigation, she was found to have hyperleukocytosis and thrombocytopenia due to acute myelogenous leukemia (AML), likely resulting in coagulopathy, vessel friability, and consequential intraparenchymal bleed. Prior reports of AML presenting with ICH are scant in the literature. As such, a heightened awareness of such a phenomenon is recommended for rapid detection and appropriate tailored management. This hopefully would, in turn, optimize outcomes.

Keywords:
acute myelogenous leukemiablast crisishyperleukocytosisintracerebral hemorrhageleukapheresis

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