Related Experiment Videos
Preliminary studies on bacterial interference of staphylococcosis of chickens
Abstract:
Previous studies indicated that Staphylococcus epidermidis strain 115 might be an effective interfering agent in reducing the rate of staphylococcosis in turkeys. In the present study, strain 115 was avirulent when administered to 3-day-old chicks by oral, aerosol, or intravenous route. Strain 115 adhered specifically to tracheal, lung, air-sac, and liver cells in vitro and interfered with subsequent colonization by virulent Staphylococcus aureus. In vivo colonization of lungs and livers of young chicks occurred following exposure to aerosols of strain 115. Strain 115 interfered with the in vivo colonization of lungs and livers by virulent S. aureus.
Insights
Staphylococcus epidermidis strain 115 is avirulent and can prevent Staphylococcus aureus colonization in chicks. This study shows its potential as a probiotic to control staphylococcosis in poultry.
Area of Science:
- Veterinary Microbiology
- Poultry Diseases
- Bacterial Interference
Background:
- Staphylococcosis is a significant concern in turkey and poultry farming.
- Staphylococcus epidermidis strain 115 previously showed potential as an interfering agent against staphylococcosis.
Purpose of the Study:
- To evaluate the safety and efficacy of Staphylococcus epidermidis strain 115 in young chicks.
- To determine if strain 115 can interfere with Staphylococcus aureus colonization in vivo and in vitro.
Main Methods:
- Administered Staphylococcus epidermidis strain 115 to 3-day-old chicks via oral, aerosol, and intravenous routes.
- Assessed strain 115's adherence to host cells in vitro.
- Evaluated in vitro and in vivo interference with virulent Staphylococcus aureus colonization.
Main Results:
- Strain 115 demonstrated avirulence in chicks across all administration routes.
- Strain 115 specifically adhered to tracheal, lung, air-sac, and liver cells.
- In vivo and in vitro studies confirmed strain 115's ability to interfere with Staphylococcus aureus colonization in the lungs and liver.
Conclusions:
- Staphylococcus epidermidis strain 115 is safe for young chicks.
- Strain 115 effectively colonizes chick organs and competitively excludes Staphylococcus aureus.
- Strain 115 holds promise as a biological control agent for staphylococcosis in poultry.