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Updated: Sep 5, 2025

Light-Controlled Fermentations for Microbial Chemical and Protein Production
Published on: March 22, 2022
Bacterial photosynthesis: state-of-the-art in light-driven carbon fixation in engineered bacteria
Xin Meng1, Liming Liu1, Xiulai Chen1
1State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; International Joint Laboratory on Food Safety, Jiangnan University, Wuxi 214122, China; Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China.
Abstract:
Light-driven carbon fixation is a promising option for reducing carbon emissions and alleviating the energy crisis. However, light energy conversion is a major limitation for supporting efficient downstream CO2 fixation pathways. Based on biomimetic technology and synthetic biology, we elaborate on new light-driven technologies in engineered bacteria from three aspects: light energy capture, reducing power generation, and energy generation. In this review, we focus on the current progress in light-driven carbon fixation and discuss new methods with great potential for industrial bioproduction, providing guidance for the development and improvement of bacterial light-driven platforms to convert CO2 into value-added chemicals.
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