Related Experiment Video
Updated: Jul 15, 2026

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
Published on: January 5, 2018
Some effects of alcohol and simulated altitude on complex performance scores and breathalyzer readings
Abstract:
Each of 17 men was trained on 7 tasks in the Multiple Task Performance Battery and then performed over a 2-week period in four experimental sessions: ground level with and without alcohol, and simulated altitude (12,500 ft), with and without alcohol. Subjects breathed appropriate gas mixtures through oxygen masks at both ground level and altitude. Alcohol doses of 100-proof vodka mixed with juice 2.2 ml X kg-1 of body weight. Results showed no differential effect of simulated altitude on breathalyzer readings (peaks averaged 78 mg % at 12,500 ft and 77 mg % at ground level). The best performance occurred at ground level under placebo conditions; the 12,500-ft simulated altitude produced some decrement for placebo scores. Alcohol at ground level resulted in significantly impaired performance during the morning sessions; the addition of altitude to the alcohol condition further depressed performance scores, but to about the same extent that placebo scores were depressed by altitude. Thus, there was no synergistic interactive effect of alcohol and altitude on either breathalyzer readings or performance scores.
Related Concept Videos
Factors Affecting Respiration
CNS Depressants: Alcohol and Nicotine
Chemical Factors Affecting Respiration Centers
CO2 has a potent influence on respiration and is strictly regulated. Under...
Depressants
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...

