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Preparation and characterization of monoclonal antibodies specific for GoCodGdCGoCo duplex with high-anti
Biochemical and Biophysical Research Communications
|April 29, 1987
Abstract:
Monoclonal antibodies were prepared using a self-complementary oligonucleotide duplex containing cyclonucleosides with the high-anti conformation as an antigen. A competition ELISA assay showed that the monoclonal antibodies specifically recognized high-anti left-handed oligonucleotides but not oligonucleotides with B- or Z-conformation.