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Updated: Sep 5, 2025
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A Quantitative Glycomics and Proteomics Combined Purification Strategy
Published on: March 8, 2016
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Quantitative glycoproteomics of high-density lipoproteins
Xinyu Tang1, Maurice Wong2, Jennyfer Tena2
1Department of Nutrition, University of California, Davis One Shields Ave. Davis CA 9516 USA amzivkovic@ucdavis.edu.
RSC Advances
|July 8, 2022
Abstract:
In this work, we developed a targeted glycoproteomic method to monitor the site-specific glycoprofiles and quantities of the most abundant HDL-associated proteins using Orbitrap LC-MS for (glyco)peptide target discovery and QqQ LC-MS for quantitative analysis. We conducted a pilot study using the workflow to determine whether HDL protein glycoprofiles are altered in healthy human participants in response to dietary glycan supplementation.
