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Autoimmune Hepatitis Associated With Cryoglobulinemic Vasculitis
Pedro Alves da Cruz Gouveia1, Maria Teresa de Souza Portela Leal1, Sylene Rampche2
1Department of Internal Medicine, Oswaldo Cruz University Hospital, Recife, Brazil.
Abstract:
Cryoglobulinemic vasculitis presents liver abnormalities usually associated with hepatitis C. We report a case of a 27-year-old woman with cryoglobulinemia and liver dysfunction secondary to autoimmune hepatitis. The patient developed purpura on the lower extremities and elevated aminotransferases. The investigation of hepatitis C was negative. Autoimmune hepatitis was confirmed by positive ANA, hypergammaglobulinemia, and compatible histological changes. Treatment with prednisone and azathioprine regressed cutaneous vasculitis and decreased aminotransferases. This case describes a rare association of cryoglobulinemic vasculitis and autoimmune hepatitis.
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