Paradoxical herniation after decompressive craniectomy provoked by mannitol: A case report
Chuan Du1, Hua-Juan Tang2, Shuang-Ming Fan3
1Neurosurgery, the Affiliated Hospital of Chengdu University, Chengdu 610000, Sichuan Province, China.
World Journal of Clinical Cases
|July 8, 2022
Summary
Paradoxical transtentorial herniation can occur after high-dose mannitol infusion in patients with large decompressive craniectomy. Placing the patient in a supine position may be life-saving and should be attempted if symptoms arise.
Area of Science:
- Neurosurgery
- Neurology
Background:
- Paradoxical transtentorial herniation is a rare complication following cerebrospinal fluid drainage in patients with large decompressive craniectomies.
- This complication has not been previously reported after rapid intravenous mannitol infusion.


