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Thromboembolic Events in a Socio-Economically Disadvantaged Population with COVID-19 Admitted to a Medicalized Hotel
Karen Lizzette Ramírez-Cervantes1,2, Consuelo Huerta-Álvarez3, Manuel Quintana-Díaz2,4
1Department of Disease Prevention and Health Promotion, Spanish Association Against Cancer, 28040 Madrid, Spain.
Insights
Social determinants of health were not linked to COVID-19 thrombosis in a Madrid study. History of venous thromboembolism and smoking were associated with thrombosis risk.
Area of Science:
- Medical Science
- Public Health
- Epidemiology
Background:
- Limited research exists on social determinants of health (SDOH) in COVID-19-related thrombosis.
- This study investigated thrombosis in socially disadvantaged populations with COVID-19.
Purpose of the Study:
- To explore the association between SDOH and thrombosis in COVID-19 patients.
- To identify risk factors for thrombosis among migrant and Spanish populations during the COVID-19 pandemic.
Main Methods:
- A cohort of 383 patients (migrant and Spanish) admitted to a medicalized hotel in Madrid were studied.
- Demographic, medical history, and socio-economic data (income, education, living conditions) were collected.
- Thrombotic events were recorded and analyzed in relation to patient characteristics.
Main Results:
- Fourteen cases (3.6%) of thrombosis were reported.
- Thrombosis was more frequent in Spanish individuals compared to migrants (OR 5.3).
- History of venous thromboembolism (OR 8.1) and current smoking (OR 4.7) were significantly associated with thrombosis. Low income and education levels were not associated.
Conclusions:
- The studied social determinants of health were not directly associated with COVID-19-related thrombosis.
- Further research is needed to understand the complex interplay of socio-economic factors and adverse outcomes like thrombosis in COVID-19 patients.
Abstract:
Background: The social determinants of health (SDOH) of patients with COVID-19-related thrombosis have been scarcely explored. Our objective was to investigate the cases of thrombosis in a group of socially disadvantaged populations with COVID-19. Methods: We investigated the thrombotic events that occurred in a cohort of migrant and Spanish patients with COVID-19 that were admitted to a medicalized hotel in Madrid. Demographic data, past medical history, and socio-economic backgrounds, such as monthly household income, level of education, and living conditions, were explored to determine the factors related to thrombosis. Results: A cohort of 383 subjects (mean age 55.4 ± 14.6 years old, 69% male), of which 58% were migrants, was studied. Fourteen (3.6%) cases of thrombosis were reported. Thrombosis was more frequent in Spanish than in migrant individuals (OR 5.3, 95%CI 1.4-19.5, p = 0.005). Neither a low monthly household income nor a low education level showed a statistical association with thrombosis (p ≥ 0.05). History of venous thromboembolism (OR 8.1, 95%CI 2.2-28.6) and being a current smoker (OR 4.7, 95%CI 1.3-16.0) were factors associated with thrombosis. Conclusions: The SDOH studied were not associated with thrombosis; however, further investigation must be performed to investigate the socio-economic conditions of subjects with COVID-19 with adverse outcomes such as thrombotic events.
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