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Updated: Sep 5, 2025

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
Laryngopharyngeal Reflux: The Last Decade
Petros D Karkos1, Jerome R Lechien2
11st Academic ORL Department, AHEPA University Hospital, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Laryngopharyngeal reflux (LPR) has long been debated for its impact on the upper aerodigestive tract. This research clarifies LPR's effects and ongoing controversies in the field.
Area of Science:
- Otolaryngology
- Gastroenterology
- Speech and Language Pathology
Background:
- Laryngopharyngeal reflux (LPR) has been a subject of extensive debate for over 30 years.
- Understanding the precise mechanisms and clinical manifestations of LPR remains challenging.
- The consequences of LPR on the upper aerodigestive tract are a significant area of ongoing research.
Discussion:
- The diagnostic criteria and therapeutic approaches for LPR continue to evolve.
- Differentiating LPR from other conditions affecting the larynx and pharynx is crucial.
- The multifactorial nature of LPR necessitates a comprehensive evaluation.
Key Insights:
- LPR involves the retrograde movement of gastric contents into the laryngopharynx.
- Symptoms may include chronic cough, throat clearing, hoarseness, and dysphagia.
- Objective diagnostic markers for LPR are still under investigation.
Outlook:
- Further research is needed to establish definitive diagnostic standards for LPR.
- Investigating the long-term effects of LPR on laryngeal health is essential.
- Developing targeted therapies for LPR will improve patient outcomes.
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