Related Experiment Video
Updated: Sep 5, 2025

Software for Analysis of Heart Rate and Blood Pressure Time-series Data from the Valsalva Maneuver
Published on: June 27, 2025
Associations between Heart Rate Variability Parameters and Hemodynamic Profiles in Patients with Primary Arterial
Małgorzata Maciorowska1, Paweł Krzesiński1, Robert Wierzbowski1
1Department of Cardiology and Internal Diseases, Military Institute of Medicine, ul. Szaserów 128, 04-141 Warsaw, Poland.
Background:
Autonomic nervous system (ANS) dysfunction is an important factor in the development and progression of arterial hypertension (AH) and may produce adverse hemodynamic sequelae. ANS function can be evaluated by analyzing heart rate variability (HRV). The purpose of this study was to assess the possible correlation between HRV and the hemodynamic profile of AH patients, including antihypertensive treatment effects after 12 months.
Methods:
The study was conducted on 144 patients with uncomplicated AH. The hemodynamic profile was assessed via echocardiography and impedance cardiography (ICG). The analyzed HRV parameters included SDNN, rMSSD, pNN50, low frequency (LF, 0.05-0.15 Hz), high frequency (HF, 0.15-0.4 Hz), total power (TP, the variance of all NN intervals), and the day, night, and 24-h low-to-high frequency ratios (LF/HF).
Results:
Analysis showed various correlations of HRV parameters both with arterial blood pressure and with the hemodynamic profile assessed via echocardiography and ICG. The HRV parameters of increased ANS activity showed a correlation with improved left ventricle function (LV) and lower LV afterload.
Conclusions:
Effective antihypertensive treatment demonstrated beneficial effects on both the ANS balance and the hemodynamic profile.
Related Concept Videos
Alterations in Blood Pressure
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
Hypertension and Regulation of Blood Pressure
Factors Influencing Heart Rate
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
Hypertension III: Clinical Manifestations and Diagnostic Studies
Special considerations while measuring blood pressure
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Factors affecting Blood pressure
Physiological Factors:

