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Updated: Sep 5, 2025

Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds
Published on: February 16, 2022
An Evidence-Based Review of Application Devices for Nitric Oxide Concentration Determination from Exhaled Air in the
Magdalena Wyszyńska1, Monika Nitsze-Wierzba2, Aleksandra Czelakowska2
1Department of Dental Materials, Division of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 15 Poniatowskiego Street, 40-055 Katowice, Poland.
Abstract:
The measurement of nitric oxide (NO) in exhaled air is used in diagnostics and monitoring the pathologies not only in the respiratory system but also in the oral cavity. It has shown a huge increase in its level in asthma and diseases of the oral cavity. It seems reasonable to undertake research on the impact of inflammation on the level of NO in exhaled air. The aim of the study is to make an evidence-based review of the application of NO levels in exhaled air in the diagnosis of inflammation and treatment monitoring on the basis of selected measuring devices.
Methods And Results:
This paper presents an example of the application of NO measurement in exhaled air in individual human systems. Selected measuring devices, their non-invasiveness, and their advantages are described.
Discussion:
The usefulness of this diagnostic method in pathologies of the oral cavity was noted.
Conclusions:
Measuring the level of NO in exhaled air seems to be a useful diagnostic method.
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