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Related Experiment Videos

Changes in Wolfe mammographic patterns with aging.

D Flook, R W Gilhome, J Harman

    The British Journal of Radiology
    |May 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

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    Mammographic patterns change with age, with the dense DY pattern often evolving to P2 or P1 in older women. This suggests age-related changes in breast tissue density.

    Area of Science:

    • Radiology
    • Mammography
    • Breast Imaging

    Background:

    • Wolfe mammographic patterns classify breast tissue density.
    • Age is a known factor influencing breast tissue composition.

    Purpose of the Study:

    • To investigate age-related changes in Wolfe mammographic patterns.
    • To determine if the DY pattern evolves with increasing age.

    Main Methods:

    • Retrospective analysis of mammograms from 212 women.
    • Comparison of mammographic patterns at a mean interval of 15 years.
    • Correlation of pattern changes with patient age.

    Main Results:

    • The DY pattern frequently transitioned to P2 or P1 patterns with advancing age.

    Related Experiment Videos

  • Younger women (mean age 47) were more likely to retain the DY pattern.
  • Women with DY to P2 or P1 transitions were older (mean ages 57 and 55, respectively).
  • A DY to N1 transition occurred in younger women (mean age 42).

    • Conclusions:

    • Findings support the hypothesis that perilobular connective tissue influences the DY pattern.
    • This tissue's activity peaks during the reproductive years (15-45) and declines later.
    • Age-related regression of connective tissue likely explains the observed mammographic pattern shifts.