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Updated: Sep 5, 2025

Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
Published on: February 1, 2022
Graphene-Based Electrochemical Sensors for Psychoactive Drugs
Ramin Boroujerdi1, Richard Paul1
1Faculty of Science and Technology, Talbot Campus, Bournemouth University, Fern Barrow, Poole BH12 5BB, UK.
Graphene sensors offer a sensitive, portable, and affordable alternative for detecting various drugs, revolutionizing drug detection methods. This review highlights advancements in graphene-based drug sensing over the past decade.
Area of Science:
- Materials Science
- Analytical Chemistry
- Nanotechnology
Background:
- Nanomaterial-based sensors are advancing healthcare, security, and industry.
- Graphene's high surface-to-weight ratio enhances sensor sensitivity and reliability.
- Graphene sensors are emerging as a revolutionary, cost-effective alternative to traditional drug detection methods.
Purpose of the Study:
- To review the development and applications of graphene-based sensors for drug detection over the last decade.
- To compare graphene sensors with other 2D nanomaterials for drug sensing capabilities.
- To explore direct and indirect drug measurement in various sample types.
Main Methods:
- Review of recent scientific literature on graphene-based sensors for drug detection.
- Comparative analysis of graphene sensors against other 2D materials like transition-metal dichalcogenides, hexagonal boron nitride, and MXenes.
- Examination of sensor performance in detecting specific drugs (e.g., cocaine, morphine, methamphetamine).
Main Results:
- Graphene sensors demonstrate high sensitivity and reliability in detecting a range of illicit and pharmaceutical drugs.
- Graphene's tunable properties allow for targeted molecular detection.
- Graphene sensors offer advantages in portability, ease of use, and cost-effectiveness compared to conventional techniques.
Conclusions:
- Graphene-based sensors represent a significant advancement in drug detection technology.
- Further research into graphene and other 2D materials will continue to enhance sensing capabilities.
- These sensors hold great promise for applications in medical diagnostics, environmental monitoring, and security screening.
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