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Using menopause status and 21-gene expression assay to inform chemotherapy benefit in node-positive breast cancer

Matthew G Davey1, Michael J Kerin2

  • 1The Lambe Institution of Translational Research, National University of Ireland, Galway, H91 YR71, Republic of Ireland. m.davey7@nuigalway.ie.

Breast Cancer Research and Treatment
|July 9, 2022
PubMed
Abstract

No abstract available in PubMed .

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Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
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