Cytogenetic studies of Sézary cells

Cytogenetic studies of two patients with Sézary's syndrome and of one patient with mycosis fungoides are reported. One chromosome #14 at band 14q11 was involved in chromosomal rearrangements in one patient. A review of previously reported cases shows that some chromosome abnormalities appeared nonrandomly, involving chromosomes #1, #4, #6, #7, #9, #13, #14, and #17. Abnormalities on 2p and monosomy 10 were emphasized.