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Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
Published on: January 28, 2020
Predictors of recurrent acute myocardial infarction despite successful percutaneous coronary intervention
Sang Hun Lee1, Myung Ho Jeong1,2, Joon Ho Ahn1
1Department of Cardiology, Chonnam National University Hospital, Gwangju, Korea.
Insights
Recurrent acute myocardial infarction (AMI) is a risk after initial treatment. Key predictors include diabetes, kidney problems, unusual chest pain, and multivessel disease, identified in a Korean study.
Area of Science:
- Cardiology
- Clinical Research
- Public Health
Background:
- Recurrent acute myocardial infarction (AMI) poses a significant risk for patients following their first event.
- Predictors for recurrent AMI after successful percutaneous coronary intervention (PCI) for a first AMI remain unclear.
Purpose of the Study:
- To identify independent predictors of recurrent AMI in patients who experienced their first AMI and underwent successful PCI.
Main Methods:
- Analysis of data from 9,869 patients in the Korea Acute Myocardial Infarction Registry-National Institute of Health (November 2011 - October 2015).
- Inclusion criteria: first AMI, successful PCI during hospitalization.
- Multivariable logistic regression analysis to determine significant predictors.
Main Results:
- The cumulative incidence of recurrent AMI after successful PCI was 3.6%.
- Significant predictors identified: diabetes mellitus, renal dysfunction, atypical chest pain, and multivessel disease.
Conclusions:
- Diabetes mellitus, renal dysfunction, atypical chest pain, and multivessel disease are independent predictors of recurrent AMI.
- Findings from a Korean prospective cohort study provide crucial insights for risk stratification and management.
Background/Aims:
Recurrent acute myocardial infarction (AMI) is an adverse cardiac event in patients with a first AMI. The predictors of recurrent AMI after the first AMI in patients who underwent successful percutaneous coronary intervention (PCI) have not been elucidated.
Methods:
We analyzed the data collected from 9,869 patients (63.2 ± 12.4 years, men:women = 7,446:2,423) who were enrolled in the Korea Acute Myocardial Infarction Registry-National Institute of Health between November 2011 and October 2015, had suffered their first AMI and had received successful PCI during the index hospitalization. Multivariable logistic regression analysis was performed to identify the independent predictors of recurrent AMI following the first AMI.
Results:
The cumulative incidence of recurrent AMI after successful PCI was 3.6% (359/9,869). According to the multivariable logistic regression analysis, the significant predictive factors for recurrent AMI were diabetes mellitus, renal dysfunction, atypical chest pain, and multivessel disease.
Conclusion:
In this Korean prospective cohort study, the independent predictors of recurrent AMI after successful PCI for the first AMI were diabetes mellitus, renal dysfunction, atypical chest pain, and multivessel disease.
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