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Intrathecal daptomycin use in a challenging case of Enterococcus faecium ventriculitis
Ankush Dhariwal1, Rachel Leff1, Mike Allen2
1Barts Health NHS Trust, Royal London Hospital, Whitechapel Rd, London E1 1BB, UK.
Abstract:
Treatment of ventriculitis caused by enterococci can be challenging, and antibiotic options are limited. We describe a case of device-related ventriculitis caused by vancomycin-resistant Enterococcus faecium , refractory to initial antibiotics. Our management approach included intrathecal daptomycin. There were no attributable adverse events, and the patient remained infection-free following ventriculo-peritoneal shunt insertion and cessation of antibiotics.
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