RE-Place: A Unique Project Collecting Expertise on New Approach Methodologies

Area of Science:

• Life Sciences
• Toxicology
• Biotechnology

Background:

• New Approach Methodologies (NAMs) offer alternatives to animal testing in life sciences.
• A bottom-up approach, involving local initiatives, can effectively promote NAMs adoption.
• There is a need for centralized resources to map available NAMs and expertise.

Purpose of the Study:

• To establish a comprehensive database of NAMs and associated experts in Belgium.
• To develop and refine a user-friendly online tool for data submission and access.
• To foster trust and stimulate the adoption and regulatory use of NAMs.

Main Methods:

• Development of a standardized template for collecting NAMs information.
• Creation of a web-based application for data entry and management.
• Pilot testing and expert feedback integration for tool refinement.
• Establishment of an open-access database for public consultation.

Main Results:

• The RE-Place project successfully created a central database of NAMs and experts in Belgium.
• A user-friendly online tool was developed and publicly launched after expert evaluation.
• The database facilitates easy identification of NAMs and experts across disciplines.
• Consideration of user-friendliness, data quality, and IP protection in the tool's design.

Conclusions:

• The RE-Place database serves as a valuable resource for scientists seeking NAMs and expertise.
• This initiative contributes to building confidence in NAMs and encourages their wider application.
• The project supports the reduction and potential elimination of animal testing in life sciences.