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Updated: Sep 5, 2025

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

Published on: August 24, 2019

Cardiopulmonary Exercise Testing in Patients with Post-COVID-19 Syndrome.

Leandro Barbagelata¹, Walter Masson¹, Diego Iglesias¹

¹Cardiology Department, Hospital Italiano de Buenos Aires, Tte. Gral. Juan Domingo Perón 4190 (C1199ABB), Buenos Aires, Argentina.

Medicina Clinica (English Ed.)

|July 11, 2022

Summary

Post-COVID-19 syndrome is linked to reduced exercise capacity, indicated by lower peak oxygen uptake and anaerobic threshold during cardiopulmonary exercise testing (CPET). Patients with long COVID experienced more symptoms during CPET.

Keywords:

Anaerobic threshold COVID-19 Cardiopulmonary exercise testing Peak VO2 Post-COVID-19 syndrome

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Published on: October 1, 2019

Area of Science:

Cardiology
Pulmonology
Infectious Diseases

Background:

Long-term symptoms, known as post-COVID-19 syndrome, persist after initial SARS-CoV-2 infection.
Cardiopulmonary exercise testing (CPET) is a key tool for assessing exercise capacity.

Purpose of the Study:

To analyze CPET characteristics in patients with a history of COVID-19.
To compare CPET findings between patients with and without post-COVID-19 syndrome.

Main Methods:

A cross-sectional study included 200 patients over 18 with confirmed SARS-CoV-2 infection.
CPET was performed 45-120 days post-infection.
Univariate and multivariate analyses assessed the association between CPET variables and post-COVID-19 syndrome.

Main Results:

Patients with post-COVID-19 syndrome exhibited significantly lower peak VO2 (25.8 vs. 28.8 mL/min/kg, p=0.017).
Post-COVID-19 patients were more likely to develop symptoms during CPET (52.7% vs. 13.7%, p<0.001).
A lower probability of reaching the anaerobic threshold was observed in post-COVID-19 patients (50.9% vs. 72.7%, p=0.002).

Conclusions:

Post-COVID-19 syndrome is associated with reduced peak VO2 and anaerobic threshold.
Increased symptom occurrence during CPET is noted in post-COVID-19 patients.
Further research is needed to establish the prognostic value of these CPET abnormalities.