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Evaluation of the Functional Visual Range of a Catenary Curve-Based, Extended Depth-of-Focus Contact Lens for Presbyopia.

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Related Experiment Video

Updated: Sep 5, 2025

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Reduction of Myopic Progression Using a Multifocal Soft Contact Lens: A Retrospective Cohort Study.

Jeffrey Cooper1,2, Brett O'Connor3, Thomas Aller4,5

  • 1Cooper Eye Care, New York, NY, USA.

Clinical Ophthalmology (Auckland, N.Z.)
|July 11, 2022
PubMed
Summary

Daily disposable multifocal contact lenses significantly slowed myopia progression by 85% in children and young adults over a 6-year period. Most wearers experienced substantial reductions in myopia progression and axial elongation.

Keywords:
myopiamyopia progression controlperipheral hyperopiasoft multifocal contact lenses

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Area of Science:

  • Ophthalmology
  • Optometry
  • Pediatric Eye Care

Background:

  • Myopia is a growing public health concern, particularly in children and young adults.
  • Effective myopia control strategies are crucial to prevent high myopia and associated ocular complications.
  • Extended depth of focus (EDOF) soft multifocal contact lenses offer a potential solution for myopia management.

Purpose of the Study:

  • To evaluate the efficacy of a specific daily disposable, soft multifocal contact lens with an extended depth of focus (center distance) design in controlling myopia progression.
  • To assess myopia progression over an approximately 6-year follow-up period in pediatric and young adult populations.
  • To compare the myopia progression and axial elongation in wearers of the NaturalVue Multifocal (NVMF) contact lens against a virtual control group.

Main Methods:

  • Retrospective cohort analysis of 196 patients (ages 5-20) fitted with NVMF contact lenses.
  • Data analyzed from the right eye over a 6-year period, with a significance level of P < 0.05.
  • Statistical analysis included one-way ANOVA with Tukeys post-hoc t-tests to compare outcomes with a virtual control group.

Main Results:

  • NVMF lens wear resulted in an average myopia progression reduction of approximately 0.84 D or 85% compared to baseline (P < 0.0001).
  • 91% of wearers showed decreased myopia progression, with 79% experiencing a ≥70% reduction.
  • Significantly lower myopic refractive error progression and axial elongation were observed in NVMF wearers compared to a virtual control group over 12, 24, and 36 months.

Conclusions:

  • Daily disposable soft multifocal contact lenses with an EDOF design are effective in reducing myopia progression in children and young adults.
  • Significant and sustained reductions in myopia progression were observed over a 6-year follow-up period.
  • NVMF contact lenses represent a viable option for myopia management in pediatric and young adult populations.