Related Experiment Video
Updated: Aug 17, 2026

Programmed Electrical Stimulation in Mice
Published on: May 26, 2010
Gap in bundle-branch conduction elicited by programmed His bundle stimulation
Abstract:
The gap phenomenon in right bundle-branch conduction was elicited during programmed stimulation of the His bundle. Premature beats with short and long coupling intervals showed undisturbed intraventricular conduction, while the premature beat with intermediate coupling interval blocked within the right bundle branch. The electrophysiologic mechanism of "supernormal" conduction of the earliest beats was conduction delay at a proximal site within the His bundle which allowed recovery of the right bundle branch. This study shows that programmed His bundle stimulation is a valuable method in analyzing conduction characteristics of the distal atrioventricular conduction system in cases where atrioventricular nodal refractoriness would preclude this by atrial stimulation.
More Related Videos
Related Concept Videos
The Cardiac Cycle
The Process
Electrical signals—sent from the sinoatrial (SA) node in the right atrial wall to the atrioventricular (AV) node between the right atrium and right ventricle—cause both atria to simultaneously contract. When the signal reaches the AV node, it pauses for approximately a tenth of a second, allowing the atria to contract and empty blood into the...
Electrophysiology of Normal Cardiac Rhythm
Conduction System of the Heart
The pacemaker cells are located in two primary nodes: the sinoatrial (SA) node and the atrioventricular (AV) node. The SA node pacemaker cells can autonomously depolarize, triggering an action potential that leads to the...
Conduction System of the Heart
This system relies on the unique properties of nodal and Purkinje cells:...
Cardiac Action Potential
The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials
Dysrhythmias IV: Characteristics of Bradyarrhythmias

