Related Experiment Video
Updated: Sep 5, 2025
A Simple Mechanical Procedure to Create Limbal Stem Cell Deficiency in Mouse
Published on: November 17, 2016
Long-Term Comprehensive Management of Bilateral Limbal Stem Cell Deficiency Secondary to Severe Chemical Burn: 10
Piero Carletti1, Paula A Sepulveda Beltran1, Harry Levine1
1Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.
Purpose:
To describe the long-term management of bilateral limbal stem cell deficiency secondary to a severe chemical burn.
Methods:
Descriptive case report.
Importance:
This case highlights the importance of early intervention in ocular chemical burns for the preservation of tissue integrity and avoidance of perforation. We also review the use of proper ocular surface reconstructive techniques to restore the function of the limbal area, as well as the immunomodulatory strategies and follow-up needed for these interventions.
