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Healing of a Large Bone Defect Secondary to Tuberculosis in an Infant: A Case Report

Rahul Hemant Shah1, Viraj N Gandbhir2, Harshad Gujar2

  • 1Department of Orthopaedics, GMERS Medical College & Hospital, Valsad, India.

JBJS Case Connector
|July 11, 2022
PubMed

Insights

Pediatric tuberculosis of the distal radius can lead to significant bone defects. This case demonstrates remarkable spontaneous bone regeneration in an infant, avoiding complex surgical interventions.

Area of Science:

  • Orthopedic surgery
  • Pediatric infectious diseases
  • Bone regeneration

Background:

  • Tuberculosis (TB) can affect bone, including the distal radius in infants.
  • Surgical intervention is often considered for large bony defects.
  • Distal radius metaphyseal defects pose challenges for bone healing.

Observation:

  • A 9-month-old infant presented with distal radius swelling due to tuberculosis.
  • Debridement and curettage resulted in a large metaphyseal bony defect.
  • The defect showed near-complete spontaneous filling within 3 months post-procedure.

Findings:

  • Spontaneous regeneration of a large bony defect in the distal radius metaphysis occurred in an infant.
  • No bone substitutes, grafting, or microvascular procedures were required.
  • The patient received 12 months of antituberculous therapy.

Implications:

  • This case highlights the potential for significant spontaneous bone regeneration in pediatric metaphyseal defects caused by tuberculosis.
  • Conservative management may be a viable option for such defects, reducing the need for invasive reconstructive surgery.
  • Further research into the mechanisms of spontaneous bone healing in pediatric TB osteomyelitis is warranted.
Abstract

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