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[Influence of risk factors on mortality from COVID-19]

Jorge Ayón-Aguilar1, Socorro Méndez-Martínez2, Ricardo Toledo-Tapia3

  • 1Instituto Mexicano del Seguro Social, Órgano de Operación Administrativa Desconcentrada, Coordinación Auxiliar Médica de Investigación en Salud. Puebla, Puebla, México.

Revista Medica Del Instituto Mexicano Del Seguro Social
|July 11, 2022
PubMed

Insights

Male gender is not a significant risk factor for COVID-19 mortality. However, advanced age (over 60), hypertension, diabetes, and obesity are confirmed risk factors for increased COVID-19 mortality.

Area of Science:

  • Epidemiology
  • Public Health
  • Infectious Diseases

Background:

  • COVID-19 mortality risk factors remain debated globally.
  • Previous studies show inconclusive evidence, particularly regarding male gender influence.

Purpose of the Study:

  • To identify key risk factors associated with higher mortality rates from COVID-19.
  • To clarify the role of various demographic and clinical factors in COVID-19 outcomes.

Main Methods:

  • A case-control study involving 1190 RT-PCR positive patients.
  • Analysis included demographic data, comorbidities (hypertension, diabetes, obesity, COPD, asthma), and lifestyle factors (smoking, vaccination status).
  • Multivariate logistic regression was used to assess the influence of risk factors on mortality.

Main Results:

  • No statistically significant difference in mortality was observed between genders.
  • Increased mortality was associated with age over 60 years.
  • Systemic arterial hypertension, diabetes mellitus, and obesity were significantly linked to higher COVID-19 mortality.

Conclusions:

  • Male gender is not a predictor of increased COVID-19 mortality.
  • Age over 60, hypertension, diabetes mellitus, and obesity are confirmed significant risk factors for COVID-19 mortality.
  • These findings aid in identifying high-risk populations for targeted interventions.
Abstract

Keywords:
Mortality Coronavirus Infections COVID-19Risk Factors

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