Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Neuroplasticity01:01

Neuroplasticity

735
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
735
Neural Regulation01:37

Neural Regulation

39.8K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
39.8K
Neural Circuits01:25

Neural Circuits

1.5K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
1.5K
Long-term Potentiation01:35

Long-term Potentiation

55.7K
Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
55.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Global prevalence and disability burden of brain disorders: Impact of neurological, mental, and substance use disorders.

Neuroscience and biobehavioral reviews·2026
Same author

A Novel Approach to Map the Causal Impact of Brain Stimulation on Semantic Processing With Language Models.

Neurobiology of language (Cambridge, Mass.)·2026
Same author

Effects of electric field direction on TMS-based motor cortex mapping.

Imaging neuroscience (Cambridge, Mass.)·2026
Same author

Stimulation success!? Improved response inhibition performance after prefrontal single-site and condition-and-perturb transcranial magnetic stimulation.

Cognitive, affective & behavioral neuroscience·2026
Same author

Task load modulates network interactions between bilateral fronto-parietal and cerebellar areas during verbal working memory.

iScience·2026
Same author

Dopaminergic manipulation modulates frequency-specific EEG connectivity patterns: evidence from a single dose drug challenge study.

Frontiers in neuroscience·2026

Related Experiment Video

Updated: Sep 5, 2025

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
09:01

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

Published on: May 7, 2014

10.3K

Age-related differences in the neural network interactions underlying the predictability gain.

Anna Uta Rysop1, Lea-Maria Schmitt2, Jonas Obleser2

  • 1Lise Meitner Research Group Cognition and Plasticity, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.

Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
|July 11, 2022
PubMed
Summary

Older adults maintain speech comprehension gains from sentence context, even with background noise. Ageing impacts brain network communication, not just regional brain activity, for understanding degraded speech.

Keywords:
AgeingCingulo-opercular networkEffective connectivitySemantic predictabilitySpeech in noise

More Related Videos

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
09:38

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

15.1K
Measuring Statistical Learning Across Modalities and Domains in School-Aged Children Via an Online Platform and Neuroimaging Techniques
08:05

Measuring Statistical Learning Across Modalities and Domains in School-Aged Children Via an Online Platform and Neuroimaging Techniques

Published on: June 30, 2020

7.7K

Related Experiment Videos

Last Updated: Sep 5, 2025

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
09:01

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

Published on: May 7, 2014

10.3K
Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
09:38

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

15.1K
Measuring Statistical Learning Across Modalities and Domains in School-Aged Children Via an Online Platform and Neuroimaging Techniques
08:05

Measuring Statistical Learning Across Modalities and Domains in School-Aged Children Via an Online Platform and Neuroimaging Techniques

Published on: June 30, 2020

7.7K

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Psychology

Background:

  • Speech comprehension is impaired by background noise.
  • Semantic context improves speech understanding.
  • Age-related changes in brain network interactions for speech processing are unclear.

Purpose of the Study:

  • Investigate age-related differences in brain network interactions during degraded speech processing.
  • Compare network activity in young and old adults for speech comprehension.
  • Understand how ageing affects semantic and domain-general network interplay.

Main Methods:

  • Functional neuroimaging (fMRI) was used.
  • Participants performed a sentence repetition task with varying speech intelligibility and predictability.
  • Stimulus intelligibility was adjusted to individual hearing levels.

Main Results:

  • Older adults exhibited preserved behavioral predictability gains for speech.
  • Both age groups activated similar semantic and cingulo-opercular brain regions.
  • Age-related differences were found in effective connectivity, with young adults showing excitatory connections and older adults showing inhibitory ones.

Conclusions:

  • Predictability gains in speech comprehension are maintained in older adults with individually adjusted intelligibility.
  • While brain regions are similar, ageing alters network interactions for processing degraded speech.
  • Ageing impacts brain network configuration, not solely regional activity, during challenging listening conditions.