Related Experiment Video
Updated: Sep 5, 2025

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Percutaneous Coronary Intervention in Multi-Vessel Disease
Tamim Akbari1, Rasha Al-Lamee2
1London Northwest University Hospital, Watford Road, Harrow HA1 3UJ, London, UK.
Insights
Multivessel coronary disease is a growing challenge due to obesity, diabetes, and aging. This review explores advancements in percutaneous coronary intervention for managing complex coronary artery disease.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Medicine
Background:
- Coronary artery disease (CAD) remains a leading cause of global morbidity and mortality.
- Increasing prevalence of obesity and diabetes, coupled with an aging demographic, contributes to a rise in patients with multivessel coronary disease.
- Managing complex multivessel coronary disease presents significant clinical challenges.
Purpose of the Study:
- To review the evidence supporting multivessel percutaneous coronary intervention (PCI).
- To evaluate the effectiveness of PCI in managing complex coronary artery disease.
- To cover the spectrum of stable and acute coronary syndromes.
Main Methods:
- Systematic review of existing literature.
- Analysis of evidence on percutaneous coronary intervention techniques.
- Examination of outcomes in patients with multivessel coronary disease.
Main Results:
- Recent advancements have enabled effective percutaneous management of complex coronary artery disease.
- Evidence supports the role of multivessel PCI in specific patient populations.
- PCI strategies are evolving for both stable and acute coronary syndromes.
Conclusions:
- Percutaneous coronary intervention is a viable and advancing option for multivessel coronary disease.
- Continued research is essential to optimize PCI strategies for complex CAD.
- Multivessel PCI offers effective management across various coronary syndromes.
Abstract:
Coronary disease carries significant morbidity and mortality globally. The pandemic of obesity and diabetes combined with an aging population have resulted in a significant proportion of patients with multivessel coronary disease, the management of which poses significant challenges. A number of advancements in coronary intervention have emerged in the last few years allowing effective percutaneous management of complex coronary disease. In this review we examine the evidence base underpinning multivessel percutaneous coronary intervention across the spectrum of stable and acute coronary syndromes.
Related Concept Videos
Coronary Artery Disease V: Interprofessional Care
Peripheral Artery Disease III: Interprofessional Care
Acute Coronary Syndrome IV: Interprofessional Care
Acute Coronary Syndrome III: Diagnostic Studies
Coronary Artery Disease IV: Preventive Measures
Coronary Artery Disease I: Introduction

